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VANCOUVER, BC, January 15th,2026/ - TheNewswire - BioVaxys Technology Corp. (CSE: BIOV) (FRA: 5LB) (OTCQB: BVAXF) ("BioVaxys" or the "Company") is pleased to provide an update on 1Q2026 initiatives, including collaborations and non-dilutive funding programs.
The Company is pleased to announce that it is participating in a Request for Information (RFI) solicitation issued by the US Government's Biomedical Advanced Research and Development Authority (BARDA) for transformative ‘New Vaccine Platforms’ that can enable efficient development timelines in response to emerging infectious disease threats. BARDAs mission is to accelerate medical countermeasure product and technology development to address evolving needs including pandemic influenza, emerging infectious diseases, and other biological threats. The RFI issued by BARDA is the precursor to a subsequent Request for Proposal (RFP), which is issued following BARDA’s assessment of novel vaccine platforms submitted during the RFI process. Having a role at the start during the RFI process ensures that the capabilities of BioVaxys’ DPX platform are considered when designing the development program needs for the RFP.
Through high-level introductions by the BioVaxys Board, the Company recently initiated discussions for a vaccine development collaboration with a United Nations-chartered international organization dedicated to discovery, development, and delivery of safe, effective, and affordable vaccines for global health initiatives. With a research budget of nearly US$120M, the organization is working to address unmet needs for Shigella, Hep B, Influenza, RSV, Rotavirus, ZIKA, HPV, and other globally critical pathogens. Kovan adds “Attributes of our DPX platform that are attractive to their vaccine development efforts include features such as duration of immune-activity, single-dose non-systemic delivery, shelf stability, and micro-dosing capabilities. DPX is uniquely positioned as a solution for antigen packaging and delivery for vaccines urgently needed in both the developed and developing world.” The Company anticipates further developments over the next several weeks as discussions continue.
Last month the Company shared that it was working with an additional prospective partner in the animal health field to advance a research collaboration for a proof-of-product program to evaluate a DPX™ formulation of a proprietary mRNA sequence for diseases requiring long-duration protection, such as rabies. “Since early January, we are jointly reviewing the study design and timelines for a DPX-mRNA rabies vaccine program, in anticipation that the protocol is to be finalized and shortly announced. The Company says it’s already established that DPX provides enhanced in vitro and in vivo stability of packaged mRNA, attracts a therapeutically unique subset of Antigen Presenting Cells (APCs) to the injection site for targeted uptake of mRNA by the immune system, and that immunization with DPX containing mRNA induces specific immune responses towards encoded antigen. Gaining additional preclinical data with a DPX-mRNA rabies formulation not only expands our pipeline, but we expect it to open new partnering discussions in the human mRNA vaccine space,” noted Kenneth Kovan, BioVaxys President and Chief Operating Officer.
BioVaxys recently announced positive results from a phase 1 clinical study of MVP-S with neoadjuvant hormone therapy in HR+ / HER2- stage II-III breast cancer, and positive Phase 1 study results with their DPX-SurMAGE and maveropepimut-S (MVP-S) cancer vaccines in patients with multiple previous recurrences of high grade non-muscle invasive bladder cancer (NMIBC), where treatment with either MVP-S or DPX-SurMAGE was shown to be well tolerated with both products inducing significant systemic antigen-specific T cell responses. After an average two years of follow-up post-treatment, many of these high-grade NIMBC patients were free of recurrence. This simple and well tolerated approach may be a valuable alternative to the many intravesical and systemic treatments currently being developed.
BioVaxys is reviewing data with Principal Investigators from an additional phase 1B/2 clinical study with MVP-S in a different formulation combination and anticipates results in the upcoming weeks.
The BioVaxys DPX platform is a major innovation in vaccine development that offers a solution to limitations faced by vaccines using other antigen delivery methods. The DPX platform presents antigens to the immune system using a novel non-systemic mechanism of action that does not release active ingredients at the site of the injection but rather forces an active uptake of immune cells and delivery into the lymphatic nodes. The programming of immune cells happens in vivo and offers a more efficient approach that mimics the natural function of the immune system. This "no release" mechanism allows for an active uptake of antigens into immune cells and lymph nodes for a sustained activation of the immune system in which the T cell flow is sustained over a longer duration than traditional vaccines on the market.
About BioVaxys Technology Corp.
BioVaxys Technology Corp. (www.biovaxys.com), a biopharmaceutical company registered in British Columbia, Canada, is a clinical-stage biopharmaceutical company dedicated to improving patient lives with novel immunotherapies based on the DPX™ immune-educating technology platform and it's HapTenix© tumor cell construct platform, for treating cancers, infectious disease, antigen desensitization for food allergy, and other immunological diseases. Through a differentiated mechanism of action, the DPX™ platform delivers instruction to the immune system to generate a specific, robust, and persistent immune response. The Company's clinical stage pipeline includes maveropepimut-S (MVP-S), based on the DPX™ platform, in phase IIB clinical development for advanced Relapsed-Refractory Diffuse Large B Cell Lymphoma (DLBCL) and platinum resistant Ovarian Cancer. MVP-S delivers antigenic peptides from the Survivin family, a set of well-recognized cancer antigens commonly overexpressed in advanced cancers and also delivers an innate immune activator and a universal CD4+ T cell helper peptide. MVP-S has been well tolerated and has demonstrated defined clinical benefit in multiple cancer indications as well as the activation of a targeted and sustained, Survivin-specific anti-tumor immune response. BioVaxys is also developing DPX™+SurMAGE, a dual-targeted immunotherapy combining antigenic peptides for both the Survivin and MAGE-A9 cancer proteins to elicit immune responses to these two distinct cancer antigens simultaneously, DPX™-RSV for Respiratory Syncytial Virus, DPX+rPA for peanut allergy prophylaxis, and BVX-0918, a personalized immunotherapeutic vaccine using its proprietary HapTenix© 'neoantigen' tumor cell construct platform for refractive late-stage ovarian cancer.
BioVaxys common shares are listed on the CSE under the stock symbol "BIOV" and trade on the Frankfurt Bourse (FSE: 5LB0) and in the U.S. on the OTC Markets (OTCQB: BVAXF). For more information, visit www.biovaxys.com and connect with us on X and LinkedIn.
ON BEHALF OF THE BIOVAXYS BOARD
Signed "James Passin"
James Passin, Chief Executive Officer
Phone: +1 740 358 0555
Cautionary Statements on Forward-Looking Information
This news release includes certain "forward-looking information" and "forward-looking statements" (collectively "forward-looking statements") within the meaning of applicable securities legislation. All statements, other than statements of historical fact, included herein, without limitation, statements relating to the future operating or financial performance of the Company, are forward-looking statements. Forward-looking statements are frequently, but not always, identified by words such as "expects", "anticipates", "believes", "intends", "estimates", "potential", "possible", and similar expressions, or statements that events, conditions, or results "will", "may", "could", or "should" occur or be achieved. There can be no assurance that such statements will prove to be accurate, and actual results and future events could differ materially from those expressed or implied in such forward-looking statements.
Forward-looking statements reflect the beliefs, opinions and projections on the date the statements are made and are based upon a number of assumptions and estimates, primarily the assumption that BioVaxys will be successful in developing and testing vaccines, that, while considered reasonable by BioVaxys, are inherently subject to significant business, economic, competitive, political and social uncertainties and contingencies including, primarily but without limitation, the risk that BioVaxys' vaccines will not prove to be effective and/ or will not receive the required regulatory approvals. With regards to BioVaxys' business, there are a number of risks that could affect the development of its biotechnology products, including, without limitation, the need for additional capital to fund clinical trials, its lack of operating history, uncertainty about whether its products will complete the long, complex and expensive clinical trial and regulatory approval process for approval of new drugs necessary for marketing approval, uncertainty about whether its DPX platform can be developed to produce safe and effective products and, if so, whether its vaccine products will be commercially accepted and profitable, the expenses, delays and uncertainties and complications typically encountered by development stage biopharmaceutical businesses, financial and development obligations under license arrangements in order to protect its rights to its products and technologies, obtaining and protecting new intellectual property rights and avoiding infringement to third parties and their dependence on manufacturing by third parties.
Many factors, both known and unknown, could cause actual results, performance or achievements to be materially different from the results, performance or achievements that are or may be expressed or implied by such forward-looking statements and the parties have made assumptions and estimates based on or related to many of these factors. BioVaxys does not assume any obligation to update the forward-looking statements of beliefs, opinions, projections, or other factors, should they change, except as required by applicable securities laws.
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